6VFIДЄntanasijevic A, Ueda G, Baker D, Ward AB. 6VFHДЄntanasijevic A, Ueda G, Baker D, Ward AB. 21174ДЄntanasijevic A, Ueda G, Baker D, Ward AB. 21173ДЄntanasijevic A, Ueda G, Baker D, Ward AB. 21172ДЄntanasijevic A, Ueda G, Ward AB, Baker D. 21171ДЄntanasijevic A, Ueda G, Baker D, Ward AB. Icosahedral Nanoparticle I53_dn5 presenting BG505-SOSIP. 21170ДЄntanasijevic A, Ueda G, Baker D, Ward AB. Tetrahedral nanoparticle T33_dn10 presenting BG505-SOSIP. 21169ДЄntanasijevic A, Ueda G, Baker D, Ward AB. De novo designed tetrahedral nanoparticle T33_dn2 presenting BG505-SOSIP. 21168ДЄntanasijevic A, Ueda G, Baker D, Ward AB. BG505-SOSIP-T33_dn2A nanoparticle fusion component in complex with VRC01-Fab. 21167ДЄntanasijevic A, Ueda G, Baker D, Ward AB. BG505-SOSIP-T33_dn2A nanoparticle fusion component. 21166ДЄntanasijevic A, Ueda G, Baker D, Ward AB. De novo designed icosahedral nanoparticle I53_dn5. 21165ДЄntanasijevic A, Ueda G, Baker D, Ward AB. De novo designed octahedral nanoparticle O43_dn18. 21164ДЄntanasijevic A, Ueda G, Baker D, Ward AB. De novo designed tetrahedral nanoparticle T33_dn10. 21163ДЄntanasijevic A, Ueda G, Baker D, Ward AB. De novo designed tetrahedral nanoparticle T33_dn5. 21162ДЄntanasijevic A, Ueda G, Baker D, Ward AB. De novo designed tetrahedral nanoparticle T33_dn2. 6VEHДЄntanasijevic A, Ueda G, Baker D, Ward AB. Computationally designed C3-symmetric homotrimer from HEAT repeat protein. Tailored Design of Protein Nanoparticle Scaffolds for Viral Glycoprotein Immunogens. Source data files have been provided for Figures 2, 4 and 6 specifically. All data generated or analysed during this study are included in the manuscript and supporting files. Cyro-EM structures have been deposited in the PDB under accession codes 6VFH, 6VFI, and 6VFJ. GUID:В 1A9C4200-AD84-4EC3-83E6-05C777EEC316 Data Availability StatementДiffraction data have been deposited in the PDB under accession codes 6V8E and 6VEH. Antanasijevic A, Ueda G, Baker D, Ward AB.Antanasijevic A, Ueda G, Ward AB, Baker D.

Sankaran B, Ueda G, Zwart PH, Baker D.

Multivalent protein scaffold